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New HIV Drug Has Potential for Weekly or Once-Yearly Dosing

One of the surprises at CROI 2016 was the first virological data from a new highly potent NRTI that in a slow-release formulation has the potential for annual dosing and that is undergoing research as both treatment and PrEP. In an oral late-breaker, Jay Grobler from Merck presented results from a dose-ranging study in macaques …

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Switching HIV+ Patients From Stribld to Genvoya Improved Proteinuria but Not eGFR

CROI 2016 Conference Abstract Number:  795 Safety of Tenofovir Alafenamide in Renal Impairment Author(s):  Anton Pozniak2, Jose R Arribas3, Samir K. Gupta4, Frank A. Post5, Anchalee Avihingsanon6, Gordon Crofoot7, Kenneth A. Lichtenstein8, Moti Ramgopal9, Ploenchan Chetchotisakd10, Marshall W. Fordyce11 Clinical Research, Gilead Sciences Inc, Foster City, CA, United States. 2 Chelsea and Westminster Hospital NHS Foundation Trust, London, …

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HIV Mutates Around Promising Gene Editing Technology (CRISPR-CAS 9)

HIV can defeat efforts to cripple it with CRISPR gene-editing technology, researchers say. And the very act of editing — involving snipping at the virus’s genome — may introduce mutations that help it to resist attack. At least half a dozen papers over the past three years have explored using the popular CRISPR–Cas9 gene editing …

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HIV-related wasting can have long-term consequences

HIV-related wasting can have long-term consequences People who suffered wasting in the past more vulnerable to frailty in later life Michael Carter Published: 30 November 2015 HIV-associated wasting can have a long-term impact on physical function and quality of life, according to research from the United States published in the online edition of AIDS. The research …

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HPV and HIV: What You Need to Know About Anal Cancer (Video)

Men who have anal sex with men (MSM) are more likely to get anal HPVthan men who only have sex with women. Researchers estimate that the prevalence of anal HPV among men who only have sex with women is around 15% while anal HPV prevalence for MSM is around 60%. If you add HIV into the mix, infection risk …

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Two New HIV Studies Give Access to Research Medications to People with Multi-Drug Resistance

By Nelson Vergel.  SalvageTherapies.org No one can deny that many patients can now suppress their HIV with effective antiretrovirals (ARVs) that cause fewer side effects. However, a vulnerable and often forgotten minority of people are still struggling with multi-drug resistant HIV (MDR-HIV) while they anxiously wait for access to lifesaving ARVs that would finally control …

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Webcast : Beyond the Berlin Patient- How Researchers Are Now Trying to Cure More HIV+ People

Webcast : Beyond the Berlin Patient- How Researchers Are Now Trying to Cure More HIV+ People By Nelson Vergel We all read headlines almost weekly about the latest HIV cure.   After years of being exposed to these inflamed news reports, we may get desensitized to the fact that there is actually progress being made in …

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Webcast Transcript: All You Need to Know About the Use of Truvada to Prevent HIV Infection (Pre-Exposure Prophylaxis- PrEP)

TRANSCRIPT FROM GOOGLE HANGOUT ON HIV PRE-EXPOSURE PROPHYLAXIS (PrEP) WITH DAMON JACOBS AND NELSON VERGEL Scott:           Hello everybody. Scott Sillary here with Viral Marketing. I’m here with Nelson Vergel and Damon Jacobs. Welcome to the Power Hangout. It’s going to be fantastic. Nelson, tell us a little bit about what we’re going …

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The HIV Prevention Pill: A Free Webcast on July 29, 6:30 PM (EDT)

The HIV Prevention Pill: A Free Webcast on July 29, 6:30 PM (EDT) Activists and educators Damon Jacobs and Nelson Vergel will answer questions about the use of Truvada for HIV Pre-Exposure Prophylaxis (PrEP) covering research facts, misconceptions and access of this highly effective prevention tool. This webcast is of interest to the lay person …

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Impaired sperm motility in HIV-infected men: an unexpected adverse effect of efavirenz?

Impaired sperm motility in HIV-infected men: an unexpected adverse effect of efavirenz? Frapsauce C, et al. Hum Reprod. 2015. Authors Frapsauce C1, Grabar S2, Leruez-Ville M3, Launay O4, Sogni P5, Gayet V6, Viard JP7, De Almeida M8, Jouannet P8, Dulioust E1. Author information 1Laboratoire de Biologie de la Reproduction, Hôpital Broca-Cochin-Hôtel Dieu, Assistance Publique-Hôpitaux de …

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HIV Activist Raises Hope and Warnings in New Attachment Inhibitor Trial.

Video: HIV Activist Raises Hope and Warnings in New Attachment Inhibitor Trial. Leading HIV activist Nelson Vergel raises hopes but also warns HIV salvage patients and their physicians about functional monotherapy risks in the Bristol-Meyers Squibb (BMS) new attachment inhibitor study (Fostemsavir, BMS-663068) currently enrolling (2015-2016). This innovative drug, along with Taimed’s ibalizumab, can be the …

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