HIV-associated fatigue in the era of highly active antiretroviral therapy: novel biological mechanisms?
I am convinced that our mitochondria are affected even after years off Zerit, DDI or AZT. Mitochondrial dysfunction has been widely reported with D drugs (D4T, DDI) and AZT and has been linked to lipoatrophy and metabolic problems. But I think what we ignore is the permanent effects on the mitochondria even after years of stopping those drugs. Although mitochondria DNA in fat and muscle …
