HIV Cure Research: Flush-and-Kill Cancer Drug: SAHA or VorinostatNelson Vergel
Apr 23, 2012
What is SAHA and Vorinostat? is both are different?
|Response from Mr. Vergel
SAHA (suberoylanilide hydroxamic acid) and Vorinostat are the same thing. Vorinostat was the first histone deacetylase inhibitor (HDAC) approved by the U.S. Food and Drug Administration (FDA) for the treatment of cutaneous T celllymphoma on October 6, 2006. It is manufactured by Merck. It is being used in HIV cure research to activate latent (hidden) virus out of reservoirs as part of a “shock-and-kill” approach.