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FDA Advisors Endorse Truvada to Prevent HIV Infection–But Big Questions Remain

Mark Mascolini (natap.org) An FDA advisory panel left little doubt that Truvada, the once-daily pill combining tenofovir and emtricitabine, will get its license extended to cover pre-exposure prophylaxis (PrEP) of HIV infection in adults with a high risk of picking up HIV sexually. But the thorny deliberations leading to that endorsement in a marathon 12.5-hour …

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Shionogi-ViiV Healthcare announces initial data from pivotal phase III study of dolutegravir in HIV

This drug will compete against raltegravir (Merck) and elvitegravir (Gilead).  It will be dosed once a day for treatment naive patients and twice a day for treatment experienced. Issued: Monday 02 April 2012, London, UK Press release issued by Shionogi-ViiV Healthcare LLC, a joint venture between ViiV Healthcare Ltd (a global specialist HIV company established …

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Drug Testing of HIV+ Employees and Athletes: What to Do if You Get a False Positive for Marijuana?

Anti-retroviral treatment & sports dopingApr 1, 2012 Hi,if a person who was taking anti retroviral drugs were subject to a sports doping test (but is not taking any form of performance enhancing drugs)would this show up in any way in their test? Response from Mr. Vergel Efavirenz (Sustiva) (also in Atripla) may cause false positive test for …

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Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®

This is a study required by the FDA to determine if Egrifta use in HIV+ people with diabetes can increase the risks of diabetic retinopathy. https://clinicaltrials.gov/ct2/show/NCT01591902 Diabetic retinopathy  is a complication of diabetes that affects the eyes. It’s caused by damage to the blood vessels of the light-sensitive tissue at the back of the eye …

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Looking for HIV+ Organ/Tissue Donors for Research

Facts about Organ and Tissue Donation for Research Requirements for research are different than requirements for transplant, and it is important to understand that anyone at any age may be a research donor candidate. A history of disease does not preclude donation for medical research. Scientists frequently need affected tissue in order to investigate treatments. …

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HIV Cure Research: Flush-and-Kill Cancer Drug: SAHA or Vorinostat

Apr 23, 2012 What is SAHA and Vorinostat? is both are different? Response from Mr. Vergel SAHA (suberoylanilide hydroxamic acid) and Vorinostat are the same thing. Vorinostat was the first histone deacetylase inhibitor (HDAC) approved by the U.S. Food and Drug Administration (FDA) for the treatment of cutaneous T celllymphoma on October 6, 2006. It is …

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Weight Loss Diets: High Protein Vs High Fiber

Studies have suggested that moderately high protein diets may be more appropriate than conventional low-fat high carbohydrate diets for individuals at risk of developing the metabolic syndrome and type 2 diabetes. However in most such studies sources of dietary carbohydrate may not have been appropriate and protein intakes may have been excessively high. Thus, in …

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