gene therapy

Groundbreaking Gene Therapy Study Gets The Go-Ahead By The FDA

Calimmune, a small biotechnology company, is  giving people a low dose chemo agent (as conditioning) and then infusing them with stem cells  that have been modified to inhibit the CCR5 receptor and to contain their own built-in HIV fusion inhibitor peptide, thereby blocking two sites that are essential for HIV infection.   The study is …

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Novel Cell and Gene Therapies for HIV

Although the development of cell-based and gene transfer therapies has been slow, progress in a number of areas is evident. Advances in the fields of gene-targeting strategies, T-cell-based approaches, and HSCs have been encouraging, and a series of ongoing and planned trials to establish proof of concept for strategies that could lead to successful cell …

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Immune Cells Modified by Gene Therapy Survive After a Decade in HIV+ People

What an amazing study! They have followed HIV+ people that have had T cells modified by genetic engineering and given by transfusion once during the past 11 years of study . 41 of the 43 people were still healthy 11 years later.  Their modified T cells could still be found in their bodies. Modified T …

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Pre-CROI HIV Cure Review Workshop Organized by Community Advocates- Meeting Notes

Thanks to Siegfried Schwarze, a research activist from  Germany, for writing down these notes from the meeting we had this past Sunday, March 4, 2012 in Seattle prior to CROI-2012. **************************************************************************** Sometimes the most important events don‘t take place at the conference itself but rather at  the surrounding workshops. This seemed to be the case this …

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Report of This Weekend’s HIV Cure Workshop in Seattle

A couple of months ago a rag tag group of activist–including Project Inform (represented by myself), the Treatment Action Group (TAG) and the AIDS Treatment Activists Coalition (ATAC)–reached out to some of the world’s leading HIV researchers and companies working on HIV cure research and asked them to spend an entire day with us talking …

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CD4 cell manipulation and reinfusion…will they make a difference in long term survival?

Very cool article on Matt’s CD4 cell manipulation and reinfusion Will this be a solution for people whose CD4 cells have remained low even after years of undectectable viral load? Are these “HIV resistant” CD4 cells functional in the long run? Well, Matt thinks his health has improved and he no longer has sinus infections …

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Interview with Man Who Got Cured of HIV

This link has a video of an interview with Tim Brown, the man who got cured of HIV (who I refer to as the “Berlin Patient”  in my article below). http://feedroom.businessweek.com/?fr_story=4a74617791423dc8652dd78d84817c27ba4045aa From TheBodypro.com Zinc Fingers and Gene Therapies for HIV: Mimicking the Cured Berlin Patient? By Nelson Vergel March 2, 2011 Jay Lalezari, M.D., from …

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