PrEP

Injection Every 3 Months to Prevent HIV- Study in San Francisco Enrolling Now

There’s a new clinical trial about to get started in SF looking for 25 men or transwomen who are at relatively low risk for HIV to test the safety, tolerability and acceptability of a very long acting (injected once every three months) for Pre-exposure prophylaxis (PrEP). If that sounds like you or someone you know, …

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New CDC Guidelines: People at Risk for HIV Should Consider Truvada PrEP

Healthcare providers should advise people at “substantial risk” for HIV infection about pre-exposure prophylaxis (PrEP) using tenofovir/emtricitabine, or Truvada, according to new guidelines issued by the U.S. Centers for Disease Control and Prevention (CDC). This includes HIV negative people in an ongoing sexual relationship with HIV positive partners, gay or bisexual men who have had sex …

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Monthly or Quarterly Injectable HIV Antiretrovirals Are Safe and Effective in Early Study

GSK744, an investigational integrase inhibitor, and TMC278 LA (a long-acting, injectable form of the NNRTI rilpivirine [Edurant]) both showed safety and efficacy when administered in once-monthly or once-quarterly doses, according to a study presented at IAS 2013. There were no drug-related serious adverse events and all adverse events were either mild or moderate. The phase 1 …

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FDA Advisors Endorse Truvada to Prevent HIV Infection–But Big Questions Remain

Mark Mascolini (natap.org) An FDA advisory panel left little doubt that Truvada, the once-daily pill combining tenofovir and emtricitabine, will get its license extended to cover pre-exposure prophylaxis (PrEP) of HIV infection in adults with a high risk of picking up HIV sexually. But the thorny deliberations leading to that endorsement in a marathon 12.5-hour …

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