S-Adenosyl-L-Methionine (SAMe) for Treatment of Depression, Osteoarthritis, and Liver Disease

I am convinced this supplement works for depression and fatigue. I have taken 400 mg twice a day and can definitely feel a difference the first day. Something else that I have noticed is that my hairy leukoplakia goes away within days. It can also decrease liver enzymes. However, it is contraindicated for those with bipolar disorder. It is not cheap. I get mine from Jarrow at the Houston Buyers Club.

Here is a summary of studies


I am attaching a study done in HIV


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