cure

Cost Effectiveness of Current HIV Cure Approaches

Published: November 14, 2014 DOI: 10.1371/journal.pone.0113031 Abstract Background We examined efficacy, toxicity, relapse, cost, and quality-of-life thresholds of hypothetical HIV cure interventions that would make them cost-effective compared to life-long antiretroviral therapy (ART). Methods We used a computer simulation model to assess three HIV cure strategies: Gene Therapy, Chemotherapy, and Stem Cell Transplantation (SCT), each …

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Two More Patients Are Cured of HIV- And This Time With A Less Complex Regimen

“Both the surviving patients had been receiving prolonged antiretroviral therapy and received stem cell transplants with a reduced-intensity conditioning regimen of chemotherapy designed to eradicate the cancer and eliminate the existing bone marrow. In the case of the two patients under investigation, the conditioning regimen did not include radiotherapy and it did not eliminate the …

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New HIV Eradication Study: The Use of a Personalized ImmuneTherapy (AGS-004) with a Reservoir Activating Agent

Argos Therapeutics Announces Plans for HIV Eradication Study  “To create AGS-004, ribonucleic acid (RNA) is isolated from HIV particles obtained from patients, and dendritic cells are generated from a single leukapheresis procedure. Selected RNAs are then used to “program” the dendritic cells with the patient-specific payload to trigger an immune response against the patient’s HIV …

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Report from CROI-2013- My Personal Picks

CROI 2013 Report Nelson Vergel I was happy to attend  CROI-2013 in Atlanta on March 3-6, 2013.  These are areas of great interest to me and in no way attempts to summarize the main findings reported at the conference.  For abstract information, refer to http://www.retroconference.org/AbstractSearch/default2.aspx?conf=22 A baby girl gets cured   The most popular media …

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Groundbreaking Gene Therapy Study Gets The Go-Ahead By The FDA

Calimmune, a small biotechnology company, is  giving people a low dose chemo agent (as conditioning) and then infusing them with stem cells  that have been modified to inhibit the CCR5 receptor and to contain their own built-in HIV fusion inhibitor peptide, thereby blocking two sites that are essential for HIV infection.   The study is …

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Novel Cell and Gene Therapies for HIV

Although the development of cell-based and gene transfer therapies has been slow, progress in a number of areas is evident. Advances in the fields of gene-targeting strategies, T-cell-based approaches, and HSCs have been encouraging, and a series of ongoing and planned trials to establish proof of concept for strategies that could lead to successful cell …

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Two more men with HIV now virus-free. Is this a cure?

They are still taking HIV medications, so we won’t know until after they interrupt their HIV treatment… Two More Patients HIV-Free After Bone Marrow Transplants http://abcnews.go.com/blogs/health/2012/07/26/two-more-patients-hiv-free-after-bone-marrow-transplants/ Two more men with HIV now virus-free. Is this a cure? http://www.msnbc.msn.com/id/48338421/ns/health-mens_health/t/two-more-men-hiv-now-virus-free-cure/#.UBG2nI6TNUR HIV Undetectable in 2 Men After Bone Marrow Transplants: Study http://health.usnews.com/health-news/news/articles/2012/07/26/hiv-undetectable-in-2-men-after-bone-marrow-transplants-study 2 HIV patients in Boston show …

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PoWeR Resources

I wanted to remind everyone about resources from Program for Wellness Restoration (PoWeR). Regards, Nelson Vergel Director Sites: http://www.powerusa.org/ http://www.facialwasting.org/ http://www.testosteronewisdom.com/ http://www.agingwithhiv.org/ http://www.salvagetherapies.org/ Groups: https://www.facebook.com/groups/testosteronereplacement/  http://health.groups.yahoo.com/group/PozHealth/  https://www.facebook.com/groups/egrifta/ https://www.facebook.com/HIVCure  https://www.facebook.com/PoWeRUSA  Ask questions: http://www.thebody.com/Forums/AIDS/Aging/ask.html  Twitter:  https://twitter.com/#!/nelsonvergel Doctor’s Lists, Directories, Compounding pharmacy, etc: http://powerusa.org/resources.html Upcoming: ShortcuttoShape.com

Doctors turn to cord blood transplants in hopes of curing patients with HIV

Timothy Brown made medical history when he became the first patient who was essentially cured of HIV, after receiving a stem cell transplant from a person who was genetically resistant to the infection.  Now, doctors are hoping to build on Brown’s success by treating HIV patients using cord blood units that have the same HIV-resistant …

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