Month: November 2014

Cost Effectiveness of Current HIV Cure Approaches

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Published: November 14, 2014 DOI: 10.1371/journal.pone.0113031 Abstract Background We examined efficacy, toxicity, relapse, cost, and quality-of-life thresholds of hypothetical HIV cure interventions that would make them cost-effective compared to life-long antiretroviral therapy (ART). Methods We used a computer simulation model to assess three HIV cure strategies: Gene Therapy, Chemotherapy, and Stem Cell Transplantation (SCT), each …

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Groundbreaking HIV vaccine’s effects were real – and could be made to work better

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Findings from further studies using a reformulation of the only HIV vaccine that has ever worked in a large efficacy trial were presented at the recent HIV Research for Prevention conference (HIVR4P). They showed evidence of stronger antibody responses, and in-depth analysis of these responses shows that by further developing a similar vaccine it may be …

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Prevalence and risk factors of sleep disturbances in a large HIV-infected adult population.

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Prevalence and risk factors of sleep disturbances in a large HIV-infected adult population. Authors Allavena C1, Guimard T2, Billaud E3, de la Tullaye S4, Reliquet V1, Pineau S3, Hüe H3, Supiot C1,Chennebault JM5, Michau C6, Hitoto H7, Vatan R8, Raffi F1. Author information Journal J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19576. doi: 10.7448/IAS.17.4.19576. eCollection 2014. Affiliation Abstract INTRODUCTION: Sleep disturbances are frequently reported in HIV-infected …

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