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Probiotic Visbiome improves gut barrier function in patients with HIV

“Probiotic supplementation improved the physical and immunological integrity of the intestinal mucosal barrier in HIV-1-positive patients being treated with antiretroviral therapy, according to new research.   The researchers sought to evaluate the effects of a high potency multistrain probiotic — marketed in the U.S. as Visbiome (ExeGi Pharma) and Vivomixx in Europe — on intestinal

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New HIV Drugs in the Pipeline- 2017: CROI Review by Dr Pablo Tebas

Gilead presented some data about a new capsid formation inhibitor (GS-CA1), a total new drug class that looks incredibly powerful in vitro (6) [ CROI: Discovery of Novel Potent HIV Capsid Inhibitors with Long-Acting Potential.] These compounds block the capsid formation during maturation and early after entry. They do not have cross resistance with other

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ibalizumab HIV

Ibalizumab: First Long Acting HIV Treatment Available Now Via Expanded Access

No one can deny that many patients can now suppress their HIV with effective antiretrovirals (ARVs) that cause fewer side effects. However, a vulnerable and often forgotten minority of people are still struggling with multi-drug resistant HIV (MDR-HIV) while they anxiously wait for access to lifesaving ARVs that would finally control their viral replication. Although

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Aerobic Exercise Increases Cognition and Brain Volume in HIV+ People

Background: HIV infected (HIV+) individuals are now reaching an advanced age, through stable treatment with highly active anti-retroviral therapy (HAART). However, HIV and aging are still risk factors for cognitive decline and neuropathologic deterioration seen in magnetic resonance imaging (MRI). Healthy lifestyle factors such as regular exercise may provide benefits to HIV+ individuals. Few studies

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HIV Lipodystrophy Update: Interview with Researcher Dr. Grace McComsey

HIV Lipodystrophy Update: Interview with Researcher Dr. Grace McComsey Dr. Grace McComsey has been involved in HIV research for 16 years, 12 of those as an NIH-funded principal investigator. Her work has focused on the investigations on lipodystrophy and metabolic complications in HIV. Her work was paramount in showing the link between nucleoside inhibitor-induced mitochondrial

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HIV Activists Seek to Accelerate Development of Immune Enhancing Therapies for Immunologic Non-Responders.

FOR IMMEDIATE RELEASE   For more information: Richard Jefferys Michael Palm Basic Science, Vaccines & Cure Project Director Treatment Action Group [email protected]   Nelson Vergel Program for Wellness Restoration [email protected]       PRESS RELEASE   HIV Activists Seek to Accelerate Development of Immune Enhancing Therapies for Immunologic Non-Responders.   Dialogues with FDA, scientists and

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aging with HIV

Good News in Aging with HIV

The Die is Cast at the STARTDavid Alain Wohl, MD – The University of North Carolina at Chapel Hill —————————– “HIV medicine has transitioned from an oncological mode created to manage a progressive and complicated fatal disease to a model that more closely resembles a diabetes clinic, where lab metrics are used to plot a

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Low-dose growth hormone therapy reduces inflammation in HIV-infected patients

Randomized controlled trial Lindboe JB, et al. Infect Dis (Lond). 2016 Nov-Dec. Authors Lindboe JB1, Langkilde A1, Eugen-Olsen J2, Hansen BR2,3, Haupt TH1, Petersen J1,4, Andersen O1,3. Author information 1a Optimed, Clinical Research Centre 056, Copenhagen University Hospital Hvidovre , Hvidovre , Denmark ; 2b Clinical Research Centre 056, Copenhagen University Hospital Hvidovre , Hvidovre

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